Methylated vitamins are essential for many, but for those with an MTHFR gene mutation or poor methylation, they can sometimes trigger a histamine response. Discover how genetics, inflammation, and nutrient imbalances influence histamine intolerance and why understanding your methylation pathway is key. Learn about supplements for histamine intolerance and how to support healthy methylation with B vitamins, magnesium, and folate-rich foods. ~ Didem