Reducing/eliminating high histamine trigger foods and supporting your digestion are critical first steps to reduce histamine in the body. The DAO enzyme is one crucial enzyme that helps to metabolize extracellular histamine in the body. If you implement these initial steps and are still struggling with histamine intolerance symptoms you may want to do genetic testing to find out where your susceptibilities lie in your genetics and unique ability to metabolize histamine or not. ~ Didem