When choosing a multivitamin for pregnancy, look for the active and most usable form of folate and vitamin B12. Up to 60% of women who have a mutation in the MTHFR gene have a decreased ability to convert the synthetic form of folate known as folic acid into the active form of folate, which is methylfolate, the most biologically available form of folate that is essential to support healthy cognitive development and prevention of neural tube defects. ~ Didem